Megaloblastic Anaemia in Premature Infants.
نویسندگان
چکیده
The common anaemia in premature infants is iron deficiency anaemia, but megaloblastic anaemia can also occur and here we report three such cases. Our interest in megaloblastic anaemia was stimulated by a recent case in which megaloblastic anaemia developed when a low phenylalanine diet was being given for treatment of phenylketonuria (Royston and Parry, 1962). In the discussion of this paper Royston and Parry advocated the need for more frequent marrow biopsy in the unexplained anaemias of infancy. As a result of this policy we have discovered the following cases in premature infants.
منابع مشابه
Folate deficiency in premature infants.
Zuelzer and Ogden first clearly defined the syndrome of megaloblastic anaemia in infants, which responds to folic acid, as long ago as 1946. They concluded: 'In an analysis of etiologic conditions, infections and nutritional deficiencies appear significant while age, race and possibly prematurity and maternal anemia are predisposing factors'. 5 ofthe 25 infants they described had been born prem...
متن کاملFolic acid status in premature infants.
Evidence is accumulating that premature infants run the risk of developing megaloblastic anaemia or other evidence of folic acid deficiency during the first two to three months of life (Gray and Butler, 1965; Shojania and Gross, 1964; Strelling, Blackledge, Goodall, and Walker, 1966). The present study was carried out to compare the folic acid status of premature infants during the first eight ...
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OBJECTIVE While iron deficiency is regarded as the major cause of nutritional anaemia, changes in vitamins A, B12, C and E, folic acid and riboflavin status have also been linked to its development and control. This paper provides a systematic review of vitamin supplementation trials relating to the control of nutritional anaemia. METHODS A MEDLINE search was used to find reports of vitamin s...
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متن کاملDoes Early Treatment Prevent Deafness in Thiamine-Responsive Megaloblastic Anaemia Syndrome?
Thiamine-responsive megaloblastic anaemia (TRMA; OMIM 249270) syndrome is an autosomal recessive disorder characterized by diabetes mellitus, megaloblastic anaemia, and sensorineural deafness. Progressive hearing loss is one of the cardinal findings of the syndrome and is known to be irreversible. Whether the deafness in TRMA syndrome can be prevented is not yet known. Here, we report a four-mo...
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عنوان ژورنال:
- Archives of disease in childhood
دوره 40 شماره
صفحات -
تاریخ انتشار 1965